Pharmacological Properties of Synthetic Cannabinoids, Specifics of Their Detection and Forensic Examination

Keywords: synthetic cannabinoids, psychotropic substances, endocannabinoid receptors, smoking mixtures, forensic examination, qualitative analysis, quantitative determination.

Abstract

The illegal circulation of synthetic cannabinoids intensifies criminal threats and negatively impacts vulnerable segments of the population due to their specific effects on the human psychophysiological state. This article examines the historical background of the recreational use of synthetic cannabinoids and their emergence in the illicit drug market. It presents data from contemporary neurobiological studies dedicated to these compounds.

The article analyzes both the therapeutic potential of synthetic cannabinoids and the adverse effects of their misuse in uncontrolled settings. It identifies key issues that must be addressed to resolve challenges in the forensic examination of objects containing these psychotropic substances and outlines the specific features of their detection and seizure.

Recommendations are provided for forensic experts in the field of narcotic drugs and psychotropic substances regarding the selection of chemical analysis methods for solutions or herbal mixtures that may contain synthetic cannabinoids. The article evaluates the applicability of instrumental analysis techniques for the qualitative identification and quantitative determination of target compounds, especially in the presence of masking agents or interfering processes during sample preparation and analysis.

Based on the study, both the positive and negative aspects of synthetic cannabinoid use are outlined, along with the most effective methods for their examination in laboratory and field conditions. The article also highlights prospects for further research into the long-term effects of synthetic cannabinoids on human physiological and mental health, their neurotoxicity, and mutagenic potential.

Overall, the findings contribute to the integration of pharmacological and forensic research data into practical application.

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Author Biography

O. M. Serdega, Kharkiv Scientific Research Expert-Criminalist Center of the Ministry of Internal Affairs of Ukraine

Department for the Study of Materials, Substances and Products,

Sector for the Study of Narcotic Drugs, Psychotropic Substances,

Their Analogues and Precursors (forensic expert).

References

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Vartuzov, V. V., Barikova, O. M., Posilskyi, O. O., & Dubrova, S. A. (2011). Research on synthetic cannabinoids. State Scientific Research Forensic Centre.

Kadzharyan, V., Solov’yuk, A., & Bidzilya, P. (2013). Endogenous cannabinoid system: role in the development of endocrine pathology. Zaporizhzhia Medical Journal, 2, 62–66.

Published
2025-07-22
How to Cite
Serdega, O. M. (2025) “Pharmacological Properties of Synthetic Cannabinoids, Specifics of Their Detection and Forensic Examination”, Bulletin of Kharkiv National University of Internal Affairs, 109(2). Available at: https://visnyk.univd.edu.ua/index.php/VNUAF/article/view/911 (Accessed: 29July2025).
Section
Criminal Procedure and Criminalistics; Forensic Examination; OSA